See below for a case series on the treatment of Hailey-Hailey disease (HHD) with low-dose naltrexone hydrochloride published in JAMA Dermatology. HHD is a rare, genetic dermatosis, which despite various treatment options, is difficult to control. The 3 patients examined exhibited at least an 80% reduction in extent of Hailey-Hailey disease after treatment with low-dose naltrexone. No adverse events were recorded with treatment.
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This study follows a review from Rare Genomics Institute examining the potential of low-dose naltrexone as a treatment option for patients with HHD.
Read the review here